job{ name = out/glycolysis-results #[1] default output files prefix filter_spaimr{ #Totally ignore some molecules type= no_effect blacklist = in/data/blacklist-remove.txt #[2] Remove the molecules from this list } filter_spaimr{ #Work the neighborhood of a list of molecule type = neighbor_nohub num = 1 #[3] neighborhood level (WARNING see details) max_hub = 0 roles = spaim startlist = in/data/glycolysis.txt #[4] take the neighborhood of molecules from this list blacklist = in/data/hubs/blacklist-2000.txt #[5] compute the neighborhood without using this molecules output = out/glycolysis-neighbor.txt #[6] log neighborhood results here } compute_filter_spaimr{} compute_influences{ #build an influence graph from the selected regulated reactions max_balance = 0 compute_balance = no compute_prod_by_unknown = yes } stats_influence{} cneighbor{ #search for key regulators (you can write this block multiple times, with differents output file prefix) id=out/glycolysis-key #[7] output file prefix for key regulators results targets =in/data/glycolysis.txt #[8] a list of molecules describing containing the regulated molecules observed=in/data/empty.txt #[9] a list of molecules (that may be empty), containing additionals informations on molecules variations } write_full_graph{} }#end job